Do not use this medication if you have severe kidney disease or are unable to urinate, if you have severe liver disease, or if you have low potassium levels in your blood (hypokalemia).
Before using this medication, tell your doctor if you have liver disease, kidney disease, gout, lupus, diabetes, or an allergy to sulfa drugs.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.